An investigation is underway following a fatal collision on the A40.

At approximately 20:40hrs on Sunday, 10 February police responded to a report of an aggravated burglary at a residential address in Harrow.

As part of this response, a vehicle pursuit was initiated.

The police helicopter was also called to assist.

At approximately 21:00hrs the vehicle being pursued moved onto the wrong side of the carriageway on the A40. The police vehicles did not follow.

The vehicle was then in collision with a coach near the junction with Kingsdown Avenue, W3.

There were three occupants in the vehicle.

Two people – one male and one female – were pronounced dead at the scene; a second male has been taken to hospital for treatment – condition awaits.

No reports of any other serious injuries.

London Ambulance Service and London Fire Brigade are on scene.

The Directorate of Professional Standards and the Independent Office for Police Conduct have been informed.